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(12R,19α,20R)-2,3-Didehydro-20-[[(7-Methoxy-1,3-Benzodioxol-5α-Yl)Carbonyl]Oxy]Aspidospermidine-3-Carboxylic Acid Methyl Ester CAS NO 52718-36-2


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CAS No.:52718-36-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(12R,19α,20R)-2,3-Didehydro-20-[[(7-Methoxy-1,3-Benzodioxol-5α-Yl)Carbonyl]Oxy]Aspidospermidine-3-Carboxylic Acid Methyl Ester is a complex, high-purity indole alkaloid derivative with significant value as a synthetic intermediate and reference standard. This compound matters for its role in advanced organic synthesis and pharmaceutical research, particularly in the development of novel bioactive molecules. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing new therapeutic agents or studying natural product chemistry.

Application

  • Pharmaceutical Research & Development (R&D): A key intermediate in the synthesis of novel drug candidates, particularly those targeting complex biological pathways.
  • Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in laboratories.
  • Medicinal Chemistry: Serves as a sophisticated building block for structure-activity relationship (SAR) studies and lead optimization.
  • Natural Product Synthesis: Employed in the total or semi-synthesis of complex indole alkaloids and related natural products.
  • Biochemical Research: Used as a tool compound to investigate specific enzyme interactions or receptor binding studies.
  • Fine Chemical Manufacturing: A critical intermediate for the production of specialized, high-value chemical entities.

Basic Information

Item Details
Product Name (12R,19α,20R)-2,3-Didehydro-20-[[(7-Methoxy-1,3-Benzodioxol-5α-Yl)Carbonyl]Oxy]Aspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No. 52718-36-2
Molecular Formula C31H34N2O7
Molecular Weight 546.62 g/mol
Synonyms Methyl (12R,19α,20R)-2,3-didehydro-20-{[(7-methoxy-1,3-benzodioxol-5-yl)carbonyl]oxy}aspidospermidine-3-carboxylate; Aspidospermidine-3-carboxylic acid, 2,3-didehydro-20-[[(7-methoxy-1,3-benzodioxol-5-yl)carbonyl]oxy]-, methyl ester, (12R,19α,20R)-; 52718-36-2; Methyl 20-[(7-methoxy-1,3-benzodioxol-5-carbonyl)oxy]-2,3-didehydroaspidospermidine-3-carboxylate; 20-O-(7-Methoxy-1,3-benzodioxole-5-carbonyl)vincadifformine methyl ester; Vincadifformine derivative
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Quality Control

Our (12R,19α,20R)-2,3-Didehydro-20-[[(7-Methoxy-1,3-Benzodioxol-5α-Yl)Carbonyl]Oxy]Aspidospermidine-3-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Related Substances (HPLC) Total impurities ≤ 5.0%
Residual Solvents (GC) Complies with ICH guidelines
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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