Description

Desethylaprindine is a key pharmaceutical intermediate and reference standard of significant importance in research and development. This compound is primarily utilized in the synthesis and analytical characterization of antiarrhythmic agents, offering critical value for quality control and metabolic studies. It is essential for pharmaceutical manufacturers, analytical laboratories, and research institutions focused on cardiovascular drug development and impurity profiling.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of antiarrhythmic drugs.
• Reference Standard: Used for the identification and quantification of impurities and degradation products in active pharmaceutical ingredients (APIs).
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for related therapeutic compounds.
• Analytical Method Development: Serves as a benchmark in HPLC, LC-MS, and other chromatographic techniques for method validation.
• Quality Control & Assurance: Essential for ensuring batch-to-batch consistency and regulatory compliance in drug manufacturing.
• Research Chemical: Used in academic and industrial research to study structure-activity relationships (SAR) of cardiac drugs.

Basic Information

Product Name	Desethylaprindine
CAS No.	52710-91-5
Molecular Formula	C20H28N2
Molecular Weight	296.45 g/mol
Synonyms	N-Desethylaprindine; N-Desethyl Aprindine; Aprindine Impurity C; 1-(2,3-Dihydro-1H-inden-2-yl)-N-(2,3-dihydro-1H-inden-2-yl)-3-(piperidin-1-yl)propan-1-amine; Aprindine Metabolite; 52710-91-5; UNII-7J3F8S4K0R
EINECS	Contact for details

Quality Control

Our Desethylaprindine is manufactured under strict quality management systems to ensure high purity and batch consistency. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity determination by chromatographic techniques. Certificates of Analysis (COA) detailing all specifications and test results are provided to support your regulatory compliance and research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.