Description

(Sulfobromophthalein)Glutathione Conjugate is a specialized biochemical reagent formed by the covalent linkage of sulfobromophthalein (BSP) to the tripeptide glutathione. This conjugate is of significant value in biomedical research, particularly for studying glutathione S-transferase (GST) enzyme activity and hepatic function. It serves as a critical tool for researchers and scientists in the fields of pharmacology, toxicology, and diagnostic assay development. The compound is essential for investigating detoxification pathways and developing analytical methods for liver function assessment.

Application

• Biochemical Research: Used as a specific substrate for studying the kinetics and inhibition of Glutathione S-Transferase (GST) enzymes.
• Diagnostic Development: Serves as a key reagent in the development of in vitro diagnostic assays for evaluating liver function and detoxification capacity.
• Toxicology Studies: Employed to model and assess the metabolism and conjugation of xenobiotics in hepatic systems.
• Enzyme Activity Assays: A standard compound for colorimetric or fluorometric assays measuring GST activity in cell lysates and tissue homogenates.
• Pharmacology Research: Utilized to investigate drug metabolism pathways and the role of glutathione conjugation in drug clearance.
• Reference Standard: Acts as a high-purity analytical standard for the quantification of related metabolites in biological samples via HPLC or LC-MS.

Basic Information

Product Name	(Sulfobromophthalein)Glutathione Conjugate
CAS No.	52682-84-5
Molecular Formula	C34H37BrN4O13S2
Molecular Weight	861.79 g/mol
Synonyms	BSP-Glutathione Conjugate; Sulfobromophthalein-GSH Conjugate; Bromosulfophthalein-Glutathione; Glutathione Sulfobromophthalein Conjugate; BSP-GSH; GST Substrate BSP-GSH; 3,3'-(4,5,6,7-Tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis[6-hydroxy-m-benzenedisulfonic acid] S-(2-[(carboxymethyl)amino]-1-[(carboxymethyl)amino]-2-oxoethyl) ester; 1-[Bis[3-carboxy-4-hydroxy-6-sulfo-2-naphthalenyl)methylidene]-4,5,6,7-tetrabromo-2-benzofuran-3-one Glutathione Conjugate
EINECS	Contact for details

Quality Control

Our (Sulfobromophthalein)Glutathione Conjugate is manufactured under strict quality protocols suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC purity analysis and spectroscopic identification, to ensure identity, potency, and consistency. While not intended for human therapeutic use, production adheres to general principles of Good Manufacturing Practice (GMP) for fine chemicals. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.