Description

Monodansylthiacadaverine is a specialized dansyl-labeled derivative of thiacadaverine, designed as a high-affinity fluorescent probe. This compound matters for researchers requiring precise detection and quantification of biological targets, particularly in enzymatic and binding studies. It is primarily needed by scientists in pharmaceutical R&D, biochemistry, and molecular biology for applications in fluorescence spectroscopy and assay development.

Application

• Fluorescent Labeling Agent: Used to tag proteins, peptides, and other biomolecules for detection and analysis.
• Enzyme Activity Assays: Serves as a substrate or probe in assays for transglutaminases and other amine-utilizing enzymes.
• Biomolecular Interaction Studies: Employed in fluorescence polarization (FP) and fluorescence resonance energy transfer (FRET) experiments to study binding kinetics.
• Cell Biology Research: Utilized as a tracer in cellular uptake and localization studies due to its fluorescent properties.
• Diagnostic Kit Development: A key component in the development of research-use-only (RUO) diagnostic and detection kits.
• High-Throughput Screening (HTS): Integrated into assay platforms for drug discovery to identify potential enzyme inhibitors or activators.

Basic Information

Product Name	Monodansylthiacadaverine
CAS No.	52664-04-7
Molecular Formula	C19H27N3O2S
Molecular Weight	361.50 g/mol
Synonyms	N-(5-Aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide; Dansylcadaverine analog; Thiacadaverine dansyl derivative; DTA; MDTC; 5-(Dimethylamino)-N-(5-aminopentyl)naphthalene-1-sulfonamide; Fluorescent thiacadaverine probe
EINECS	Contact for details

Quality Control

Our Monodansylthiacadaverine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic nature, the container should be kept in a desiccated environment. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 2.0%
Fluorescence Properties	Excitation/Emission maxima typical for dansyl group

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.