Description

n-(Trifluoroacetyl)-o-(Trimethylsilyl)-L-Tyrosine Trimethylsilyl Ester is a sophisticated, fully protected derivative of the amino acid L-tyrosine, designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring high-purity, reactive intermediates for peptide synthesis and pharmaceutical development. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for the production of complex peptides, peptidomimetics, and novel active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis Intermediate: Serves as a key protected building block in solid-phase and solution-phase peptide synthesis, particularly for introducing tyrosine residues.
• Pharmaceutical Research & Development: Used in the R&D of new peptide-based therapeutics, hormones, and diagnostic agents.
• Proteomics & Biochemical Research: Employed in the study of protein structure, function, and post-translational modifications.
• Production of Labeled Compounds: Acts as a precursor for the synthesis of isotopically labeled (e.g., 13C, 15N) amino acids and peptides for mass spectrometry and NMR studies.
• Fine Chemical Manufacturing: Utilized in the custom synthesis of complex organic molecules and specialty chemicals.

Basic Information

Product Name	n-(Trifluoroacetyl)-o-(Trimethylsilyl)-L-Tyrosine Trimethylsilyl Ester
CAS No.	52558-10-8
Molecular Formula	C17H26F3NO4Si2
Molecular Weight	421.56 g/mol
Synonyms	L-Tyrosine, N-[(trifluoroacetyl)-O-(trimethylsilyl)-, trimethylsilyl ester; N-(Trifluoroacetyl)-O-(trimethylsilyl)-L-tyrosine trimethylsilyl ester; N-TFA-O-TMS-L-Tyrosine TMS Ester; Fully Protected L-Tyrosine Derivative; Fmoc-Tyr(Trt)-OH related intermediate; Tyrosine TFA TMS derivative; CAS 52558-10-8
EINECS	Contact for details

Quality Control

Every batch of our n-(Trifluoroacetyl)-o-(Trimethylsilyl)-L-Tyrosine Trimethylsilyl Ester is produced and tested under strict quality management protocols to ensure consistency and reliability for critical research and production. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC), identity (by IR and NMR), and moisture content. Our quality system is designed to support applications requiring high-purity intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.