Description

Siroheme CAS NO 52553-42-1 is a specialized iron-containing isobacteriochlorin prosthetic group, a vital cofactor in the sulfite and nitrite reductase enzyme families. This compound is essential for facilitating key enzymatic reactions in the sulfur and nitrogen cycles, making it a critical component for advanced biochemical research and development. It is primarily utilized by researchers and manufacturers in the fields of enzymology, microbiology, and pharmaceutical development, particularly for studying and producing enzymes involved in detoxification and assimilation pathways.

Application

• Enzyme Research & Reconstitution: Essential for in vitro studies and functional reconstitution of sulfite and nitrite reductases.
• Microbial Metabolism Studies: Used to investigate anaerobic respiration and assimilatory pathways in bacteria and archaea.
• Biochemical Standard: Serves as a high-purity reference standard for analytical method development and calibration.
• Pharmaceutical Development: Investigated for its role in enzyme systems relevant to therapeutic targets and prodrug activation.
• Nutrient & Diagnostic Kits: Potential component in specialized cell culture media or diagnostic assays for specific metabolic functions.

Basic Information

Product Name	Siroheme
CAS No.	52553-42-1
Molecular Formula	C₄₂H₄₆FeN₄O₆
Molecular Weight	758.68 g/mol
Synonyms	Iron-sirohydrochlorin; Sirohydrochlorin iron complex; Sirohaem; [8,12-Diethenyl-3,7,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]iron; 21H,23H-Porphine-2,18-dipropanoic acid, 8,12-diethenyl-3,7,13,17-tetramethyl-, iron complex
EINECS	Contact for details

Quality Control

Our Siroheme is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analysis including HPLC for purity, spectroscopic identification (UV-Vis, IR), and metal content analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Dark red to brown powder
Identification (UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95%
Iron Content	Contact for details
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.