Description

n-Hydroxychlorphentermine is a key synthetic intermediate in the production of specialized pharmaceutical compounds. Its primary value lies in its role as a versatile building block for the development of active pharmaceutical ingredients (APIs) and for advanced research in medicinal chemistry. This compound is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of specific active pharmaceutical ingredients (APIs) and potential drug candidates.
• Medicinal Chemistry Research: Used as a building block for the design, synthesis, and structure-activity relationship (SAR) studies of new chemical entities in drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Metabolite Studies: Utilized in pharmacological and toxicological research to study drug metabolism pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.

Basic Information

Item	Details
Product Name	n-Hydroxychlorphentermine
CAS No.	52497-64-0
Molecular Formula	C10H14ClNO
Molecular Weight	199.68 g/mol
Synonyms	4-Chloro-N-hydroxy-α,α-dimethylphenethylamine; 1-(4-Chlorophenyl)-2-methyl-2-(hydroxyamino)propane; N-Hydroxy-4-chloro-α,α-dimethylphenethylamine; p-Chloro-N-hydroxyphentermine; Hydroxychlorphentermine; 52497-64-0; Chlorphentermine N-oxide (related metabolite)
EINECS	Contact for details

Quality Control

Our n-Hydroxychlorphentermine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. Recommended long-term storage at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.