Description

Acetamide, n-[(1S)-1-(Hydroxymethyl)-2-Phenylethyl]- is a chiral, non-proteinogenic amino acid derivative featuring a phenylalanine-like backbone with an acetamide functional group. This compound is of significant value as a versatile building block in organic synthesis, particularly for the preparation of peptides and other bioactive molecules where stereochemical control is critical. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of peptide-based drugs and enzyme inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new pharmacophores and optimize drug candidates.
• Asymmetric Synthesis: Serves as a starting material or precursor in catalytic asymmetric reactions to construct complex chiral molecules.
• Bioconjugation: Potential use in modifying biomolecules due to its reactive amide and hydroxyl functional groups.
• Chemical Biology Probes: Can be incorporated into probes for studying biological processes and protein interactions.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis.

Basic Information

Product Name	Acetamide, n-[(1S)-1-(Hydroxymethyl)-2-Phenylethyl]-
CAS No.	52485-51-5
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	N-[(2S)-2-Benzyl-3-hydroxypropyl]acetamide; (S)-2-(Acetylamino)-3-phenyl-1-propanol; L-2-Acetamido-3-phenyl-1-propanol; N-Acetyl-L-homophenylalaninol; N-Acetyl-L-phenylalaninol; N-[(1S)-1-(Hydroxymethyl)-2-phenylethyl]acetamide; Acetamide, N-[1-(hydroxymethyl)-2-phenylethyl]-, (S)-
EINECS	Contact for details

Quality Control

Our Acetamide, n-[(1S)-1-(Hydroxymethyl)-2-Phenylethyl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.