Description

Noroxycodone Hcl CAS NO 52446-25-0 is a high-purity pharmaceutical intermediate and reference standard of significant importance in research and development. This compound is a key synthetic precursor and metabolite in the study of opioid analgesics, offering critical value for analytical and pharmacological investigations. It is primarily required by pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions engaged in forensic science, drug metabolism studies, and the development of controlled substance detection methods.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of opioid substances in drug testing and quality control laboratories.
• Metabolite Research: Serves as a critical metabolite standard in pharmacokinetic and pharmacodynamic studies related to oxycodone and its derivatives.
• Forensic Analysis: Employed in forensic toxicology for the identification and confirmation of opioid compounds in biological samples.
• Chemical Synthesis: Acts as a key synthetic intermediate or starting material in the research-scale preparation of specialized opioid analogs for investigative purposes.
• Analytical Method Development: Utilized to develop, validate, and calibrate analytical methods such as HPLC, GC-MS, and LC-MS/MS for opioid detection.
• Regulatory Compliance Testing: Supports testing protocols to ensure compliance with drug safety and controlled substance regulations in pharmaceutical manufacturing.

Basic Information

Product Name	Noroxycodone Hydrochloride
CAS No.	52446-25-0
Molecular Formula	C17H20ClNO4
Molecular Weight	337.80 g/mol
Synonyms	Noroxycodone HCl; 14-Hydroxydihydrocodeinone, N-desmethyl-; Noroxycodone Hydrochloride; 14-Hydroxydihydrocodeinone, N-demethyl-; 4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Hydrochloride, N-desmethyl-; Noroxycodone (Hydrochloride); 14-Hydroxy-7,8-dihydrocodeinone, N-desmethyl-, Hydrochloride
EINECS	Contact for details

Quality Control

Our Noroxycodone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including identification, purity assay, and impurity profiling via advanced chromatographic techniques, to ensure it meets exacting standards for research and reference use. A comprehensive Certificate of Analysis (COA) detailing purity, results of all tests, and batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.