Description

Tri-o-Acetyl-D-Xylopyranosyl Cyanide is a key protected glycosyl donor and synthetic intermediate in carbohydrate chemistry. This compound is valued for its role in the stereoselective construction of glycosidic bonds, enabling the synthesis of complex oligosaccharides and nucleoside analogs. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and advanced biomaterials.

Application

• Glycosylation Reactions: Acts as a crucial glycosyl donor for the synthesis of C-glycosides and O-glycosides with high stereochemical control.
• Nucleoside Analog Synthesis: Serves as a key building block in the preparation of modified nucleosides with potential antiviral or anticancer activity.
• Oligosaccharide Assembly: Used in the iterative construction of complex carbohydrate chains for biological studies and drug discovery.
• Glycoconjugate Development: Employed in creating glycopeptides, glycolipids, and other conjugates for immunological and biochemical research.
• Chiral Intermediate: Provides a chiral scaffold for the synthesis of other fine chemicals and specialty materials.
• Process Chemistry: Applied in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Tri-o-Acetyl-D-Xylopyranosyl Cyanide
CAS No.	52443-06-8
Molecular Formula	C12H15NO7
Molecular Weight	285.25 g/mol
Synonyms	2,3,4-Tri-O-acetyl-α-D-xylopyranosyl cyanide; 1-Cyano-2,3,4-tri-O-acetyl-α-D-xylopyranose; (2R,3S,4R,5R)-5-(Cyanomethyl)-2,3,4-tris(acetyloxy)tetrahydro-2H-pyran; Triacetyl-D-xylopyranosyl cyanide; α-D-Xylopyranosyl cyanide 2,3,4-triacetate
EINECS	Contact for details

Quality Control

Our Tri-o-Acetyl-D-Xylopyranosyl Cyanide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.