Description

Dl-n-Benzoyl-2-Isopropylserine CAS NO 52421-46-2 is a synthetic, non-proteinogenic amino acid derivative characterized by its benzoyl-protected serine backbone with an isopropyl side chain. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis, enabling the production of complex molecules with high stereochemical fidelity. It is primarily utilized by research institutions and pharmaceutical manufacturers developing novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the synthesis of modified peptides and peptide mimetics, where the protected serine moiety and isopropyl group introduce specific steric and functional properties.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric reactions to construct complex chiral centers.
• Biochemical Research: Employed as a standard or reagent in studies involving enzyme inhibition, substrate specificity, and metabolic pathway analysis.
• Fine Chemical Production: An intermediate in the manufacture of specialty chemicals, including advanced materials, ligands for catalysis, and custom-designed molecular entities.

Basic Information

Product Name	Dl-n-Benzoyl-2-Isopropylserine
CAS No.	52421-46-2
Molecular Formula	C14H19NO4
Molecular Weight	265.31 g/mol
Synonyms	DL-N-Benzoyl-2-isopropylserine; (±)-N-Benzoyl-2-isopropylserine; 2-Isopropyl-3-(benzoylamino)-3-hydroxypropanoic acid; Benzoyl-isopropylserine; Bz-Ips-OH; N-Benzoyl-α-isopropylserine; N-(Benzoyl)-2-isopropylserine; 52421-46-2
EINECS	Contact for details

Quality Control

Our Dl-n-Benzoyl-2-Isopropylserine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.