Description

1-Bromo-4-(1,1,2,3,3,3-Hexafluoropropoxy)Benzene is a high-value fluorinated aromatic building block, distinguished by its unique hexafluoropropoxy side chain. This compound is engineered to provide exceptional chemical stability and specific reactivity, making it a critical intermediate for advanced synthesis. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials sectors for constructing complex molecules where fluorine incorporation is desired to modulate properties like bioavailability, lipophilicity, and environmental stability.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic ether motifs to enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs), influencing dielectric constant and charge transport properties.
• Polymer & Resin Modifier: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced resistance to solvents, heat, and UV degradation.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitutions to create complex, multi-functional aromatic systems for research.

Basic Information

Item	Detail
Product Name	1-Bromo-4-(1,1,2,3,3,3-Hexafluoropropoxy)Benzene
CAS No.	52328-78-6
Molecular Formula	C9H5BrF6O
Molecular Weight	323.03 g/mol
Synonyms	4-Bromo-1-(1,1,2,3,3,3-hexafluoropropoxy)benzene; p-Bromo(1,1,2,3,3,3-hexafluoropropoxy)benzene; 1-Bromo-4-(hexafluoroisopropoxy)benzene; Benzene, 1-bromo-4-(1,1,2,3,3,3-hexafluoropropoxy)-; 4-Bromophenyl hexafluoroisopropyl ether; (4-Bromophenoxy)(1,1,2,3,3,3-hexafluoropropyl) ether
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(1,1,2,3,3,3-Hexafluoropropoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.