Description

Aristolochic Acid-I, Sodium Salt is a high-purity, standardized sodium salt derivative of a key aristolochic acid compound. This product is essential for researchers and quality control laboratories requiring a consistent and well-characterized reference material for analytical and pharmacological studies. It is primarily utilized in the pharmaceutical, toxicology, and life science research sectors for method development, validation, and investigative purposes.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the identification and quantification of aristolochic acids in herbal medicines, dietary supplements, and pharmaceutical products.
• Toxicological Research: Used in in vitro and in vivo studies to investigate the nephrotoxic and carcinogenic mechanisms associated with aristolochic acid exposure.
• Analytical Method Development: A critical component for developing and validating high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), and other analytical methods.
• Quality Control & Assurance: Employed in QC laboratories to test raw materials and finished products for the presence of regulated aristolochic acid contaminants, ensuring compliance with safety regulations.
• Biochemical Research: Utilized as a tool compound to study DNA adduct formation, mutagenesis, and related biochemical pathways in cellular models.

Basic Information

Product Name	Aristolochic Acid-I, Sodium Salt
CAS No.	52232-70-9
Molecular Formula	C17H11NO7Na
Molecular Weight	364.27 g/mol
Synonyms	Aristolochic Acid A Sodium Salt; Sodium Aristolochate-I; 8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic Acid Sodium Salt; Aristolochic Acid I Sodium; Aristolochic Acid Sodium Salt (Type A); Nitrophenanthrene carboxylic acid sodium salt
EINECS	Contact for details

Quality Control

Our Aristolochic Acid-I, Sodium Salt is produced under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and reference standards. A detailed Certificate of Analysis (COA) containing batch-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.