Description

Cefrotil CAS NO 52231-20-6 is a semi-synthetic cephalosporin antibiotic belonging to the second-generation class. This compound is valued for its broad-spectrum activity against a range of Gram-positive and Gram-negative bacteria, offering enhanced stability against β-lactamases. It is primarily utilized in the pharmaceutical industry for the research, development, and synthesis of advanced antibacterial formulations. Its properties make it a critical intermediate and active pharmaceutical ingredient (API) for addressing complex microbial infections.

Application

• Pharmaceutical API Synthesis: Serves as a key intermediate or active ingredient in the manufacture of injectable and oral cephalosporin antibiotics.
• Veterinary Medicine: Used in the development of antibacterial treatments for livestock and companion animals.
• Clinical Research: Employed in microbiological and pharmacological studies to evaluate efficacy against resistant bacterial strains.
• Reference Standard: Functions as a high-purity analytical standard for quality control and regulatory testing in laboratories.
• Formulation Development: Integral to creating stable and bioavailable dosage forms, including powders for suspension.

Basic Information

Product Name	Cefrotil
CAS No.	52231-20-6
Molecular Formula	C20H21N5O7S2
Molecular Weight	507.54 g/mol
Synonyms	Cefrotil; Cefrotilum; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefmenoxime Impurity C; Antibiotic 64716-S
EINECS	Contact for details

Quality Control

Our Cefrotil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and stringent control of related substances and residual solvents. We provide Certificates of Analysis (COA) that detail compliance with in-house specifications and support its use in GMP (Good Manufacturing Practice) environments for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0 %
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 2.0 %
Residue on Ignition	≤ 0.2 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.