Description

Chondroitinase B is a highly specific lyase enzyme that catalyzes the eliminative cleavage of dermatan sulfate (chondroitin sulfate B). This product is essential for research and development in the life sciences, enabling precise structural analysis and functional studies of glycosaminoglycans (GAGs). It is a critical reagent for biochemists, molecular biologists, and pharmaceutical researchers focused on connective tissue biology, neurobiology, and therapeutic development.

Application

• Glycosaminoglycan (GAG) Analysis: Used for the specific depolymerization and structural elucidation of dermatan sulfate chains in proteoglycans.
• Biomedical Research: A key tool for studying the role of dermatan sulfate in cell signaling, wound healing, and disease pathology.
• Neurobiology Studies: Employed in experimental models to degrade chondroitin sulfate proteoglycans (CSPGs) and investigate neural plasticity and regeneration.
• Pharmaceutical Development: Used in the R&D of enzyme-based therapies and for characterizing biopharmaceutical products derived from or targeting connective tissue.
• Diagnostic Reagent Manufacturing: Serves as a component in diagnostic kits for the detection and quantification of specific GAGs.

Basic Information

Product Name	Chondroitinase B
CAS No.	52227-83-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Chondroitin B lyase; Chondroitinase B from *Flavobacterium heparinum*; Chondroitin sulfate B lyase; Chondroitin ABC lyase B; Dermatan sulfate lyase; EC 4.2.2.19; Chondroitinase B enzyme
EINECS	Contact for details

Quality Control

Our Chondroitinase B is produced and tested under stringent quality management systems. Each lot undergoes comprehensive analytical testing to ensure high purity, specific activity, and functional consistency. A detailed Certificate of Analysis (COA), providing data on activity, purity, and absence of contaminating activities, is available for every batch to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Activity)	Conforms
Specific Activity	≥ 10 units/mg protein
Purity (SDS-PAGE)	≥ 90%
Protein Content (Biuret)	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in water or appropriate buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.