Description

Cephalexin Sulfoxide is a key pharmaceutical intermediate and oxidative derivative of the first-generation cephalosporin antibiotic, Cephalexin. Its primary value lies in its role as a critical precursor in the synthesis and research of advanced β-lactam antibiotics, enabling the development of novel therapeutic agents. This compound is essential for manufacturers and research institutions in the pharmaceutical and biotechnology sectors focused on antibiotic development, impurity profiling, and analytical method validation.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of advanced cephalosporin derivatives and novel β-lactam compounds.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control, method development, and impurity identification in Cephalexin API and finished drug products.
• Research & Development: Serves as a key substrate in metabolic studies, stability testing, and research into the degradation pathways of cephalosporin antibiotics.
• Impurity Standard: Employed to quantify and qualify Cephalexin Sulfoxide as a known impurity or degradation product in compliance with ICH guidelines for pharmaceutical impurities.
• Process Chemistry: Utilized in process optimization and scale-up studies for Cephalexin manufacturing, helping to control and understand oxidative by-products.

Basic Information

Product Name	Cephalexin Sulfoxide
CAS No.	52210-38-5
Molecular Formula	C16H17N3O5S
Molecular Weight	363.39 g/mol
Synonyms	(6R,7R)-7-[(2R)-2-Amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 5-oxide; Cephalexin S-oxide; Cephalexin Sulfoxide; Cefalexin Sulfoxide; Cephalexin Impurity F (Sulfoxide); 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(aminophenylacetyl)amino]-3-methyl-8-oxo-, 5-oxide, [6R-[6α,7β(R*)]]-; Cephalexin related compound F
EINECS	Contact for details

Quality Control

Our Cephalexin Sulfoxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and related substances, IR and NMR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all test results against predefined specifications. Our quality commitment ensures the material is suitable for use as a pharmaceutical intermediate and reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.