Description

2-[(Dimethylamino)Methylene]-3-(4-Bromophenyl)-3-Oxo-Propanenitrile is a specialized organic intermediate featuring a bromophenyl group and a reactive cyanoenamine moiety. This compound matters for its role as a versatile building block in the synthesis of complex heterocyclic and pharmaceutical compounds. It is needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced material industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing pyridine, pyrimidine, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the reactivity of the bromine substituent for further functionalization.
• Material Science Research: Serves as a monomer or building block for creating functional organic materials, such as organic semiconductors or ligands for metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Dye and Pigment Intermediate: Acts as a starting material for the production of specialized dyes and organic pigments due to its conjugated system.
• Academic and Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	2-[(Dimethylamino)Methylene]-3-(4-Bromophenyl)-3-Oxo-Propanenitrile
CAS No.	52200-18-7
Molecular Formula	C₁₂H₁₁BrN₂O
Molecular Weight	279.13 g/mol
Synonyms	3-(4-Bromophenyl)-2-[(dimethylamino)methylene]-3-oxopropanenitrile; 2-(Dimethylaminomethylene)-3-(4-bromophenyl)-3-oxopropanenitrile; 3-(4-Bromobenzoyl)-2-(dimethylaminomethylene)propanenitrile; Propanenitrile, 2-[(dimethylamino)methylene]-3-(4-bromophenyl)-3-oxo-; (2Z)-2-[(Dimethylamino)methylidene]-3-(4-bromophenyl)-3-oxopropanenitrile
EINECS	Contact for details

Quality Control

Our 2-[(Dimethylamino)Methylene]-3-(4-Bromophenyl)-3-Oxo-Propanenitrile undergoes rigorous quality testing to ensure compliance with industry standards for research and process chemistry. We implement strict in-process controls and final batch analysis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.