Description

2-[(Dimethylamino)Methylene]-3-(4-Chlorophenyl)-3-Oxo-Propanenitrile is a versatile and high-value chemical intermediate characterized by its unique molecular structure featuring a chlorophenyl ring and a reactive cyanoenamine moiety. This compound is crucial for the synthesis of complex heterocyclic systems and active pharmaceutical ingredients (APIs), offering a strategic building block for advanced organic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various heterocyclic compounds with potential biological activity, including quinolones, pyridines, and other nitrogen-containing pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the reactivity of its functional groups to create new active molecules.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized organic dyes and pigments, where the chlorophenyl group contributes to color fastness and stability.
• Material Science Research: Employed in the development of advanced organic materials, such as organic semiconductors or non-linear optical (NLO) materials, due to its conjugated system.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, particularly in reactions involving cyano, keto, and enamine functionalities.

Basic Information

Product Name	2-[(Dimethylamino)Methylene]-3-(4-Chlorophenyl)-3-Oxo-Propanenitrile
CAS No.	52200-16-5
Molecular Formula	C₁₂H₁₁ClN₂O
Molecular Weight	234.68 g/mol
Synonyms	3-(4-Chlorophenyl)-2-[(dimethylamino)methylene]-3-oxopropanenitrile; 2-(Dimethylaminomethylene)-3-(4-chlorophenyl)-3-oxopropanenitrile; 3-(p-Chlorophenyl)-2-(dimethylaminomethylene)-3-oxopropanenitrile; Propanenitrile, 2-[(dimethylamino)methylene]-3-(4-chlorophenyl)-3-oxo-; (2Z)-2-[(Dimethylamino)methylidene]-3-(4-chlorophenyl)-3-oxopropanenitrile; 4-Chloro-α-[(dimethylamino)methylene]benzeneacetonitrile; A key intermediate for Ciprofloxacin analogs
EINECS	Contact for details

Quality Control

Our 2-[(Dimethylamino)Methylene]-3-(4-Chlorophenyl)-3-Oxo-Propanenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.