Description

3-(Dimethylamino)-2-(2-Fluorobenzoyl)Acrylonitrile is a specialized acrylonitrile derivative featuring a fluorinated benzoyl group and a dimethylamino substituent, making it a valuable building block in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and functional materials due to its unique reactivity profile. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Functional Material Development: Serves as a monomer or cross-linking agent in the creation of specialty polymers with tailored optical or electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development and as a scaffold for creating diverse chemical libraries.
• Ligand and Catalyst Preparation: Utilized in the synthesis of complex ligands for catalysis or as a component in organometallic chemistry.

Basic Information

Product Name	3-(Dimethylamino)-2-(2-Fluorobenzoyl)Acrylonitrile
CAS No.	52200-14-3
Molecular Formula	C₁₂H₁₁FN₂O
Molecular Weight	218.23 g/mol
Synonyms	2-(2-Fluorobenzoyl)-3-(dimethylamino)acrylonitrile; (2E)-3-(Dimethylamino)-2-[(2-fluorophenyl)carbonyl]prop-2-enenitrile; 2-Fluoro-α-[(dimethylamino)methylene]benzeneacetonitrile; 3-Dimethylamino-2-(2-fluorobenzoyl)acrylonitrile; DNFA; Acrylonitrile, 3-(dimethylamino)-2-(2-fluorobenzoyl)-
EINECS	Contact for details

Quality Control

Our 3-(Dimethylamino)-2-(2-Fluorobenzoyl)Acrylonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.