Description

8-Hydroxymethylriboflavin is a chemically modified derivative of riboflavin (Vitamin B2), characterized by the introduction of a hydroxymethyl group at the 8-position of the isoalloxazine ring. This structural modification is of significant interest for its role as a key intermediate in the synthesis of advanced riboflavin analogs and coenzymes. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, nutraceutical, and fine chemical sectors for developing novel biochemical tools and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel riboflavin derivatives and flavin mononucleotide (FMN) analogs with potential therapeutic applications.
• Biochemical Research: Used as a precursor in enzymatic and metabolic studies to investigate flavoprotein mechanisms and develop enzyme inhibitors.
• Nutraceutical Development: Employed in research for creating advanced vitamin B2 formulations with enhanced bioavailability or specific functional properties.
• Fine Chemical Synthesis: Acts as a specialized intermediate in the multi-step synthesis of complex organic molecules for academic and industrial research.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for HPLC or LC-MS method development and validation.

Basic Information

Product Name	8-Hydroxymethylriboflavin
CAS No.	52134-62-0
Molecular Formula	C17H20N4O7
Molecular Weight	392.36 g/mol
Synonyms	8-(Hydroxymethyl)riboflavin; Vitamin B2 8-hydroxymethyl derivative; 8-HMR; 8-Hydroxymethyl-7,8-dimethyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione; Lumiflavin 8-hydroxymethyl derivative; 8-CH2OH-Riboflavin
EINECS	Contact for details

Quality Control

Our 8-Hydroxymethylriboflavin is produced under controlled conditions to ensure high chemical purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity determination, and is supplied with a comprehensive Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support its use in research and development for regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.