Description

2-Iodo-3-Methylbenzonitrile is a versatile halogenated aromatic nitrile compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and a nitrile group on a methylated benzene ring, makes it a valuable intermediate for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the iodo-methylbenzonitrile scaffold provides specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Material Science Research: Building block for organic electronic materials, liquid crystals, and polymers where its halogen and nitrile functionality can tune electronic properties.
• Chemical Research & Development: A versatile reagent for exploring new organic transformations and constructing complex heterocyclic compounds in academic and industrial R&D settings.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	2-Iodo-3-Methylbenzonitrile
CAS No.	52107-70-7
Molecular Formula	C8H6IN
Molecular Weight	243.05 g/mol
Synonyms	3-Methyl-2-iodobenzonitrile; 2-Iodo-3-methylbenzonitrile; 2-Cyano-6-iodotoluene; 6-Iodo-o-tolunitrile; Benzonitrile, 2-iodo-3-methyl-; o-Tolunitrile, 6-iodo-; 2-Iodo-3-tolunitrile
EINECS	Contact for details

Quality Control

Our 2-Iodo-3-Methylbenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity while monitoring for specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.