Description

Cefamandole Sodium is a second-generation cephalosporin antibiotic available in its sodium salt form for enhanced stability and solubility. This compound is valued for its broad-spectrum bactericidal activity against a range of Gram-positive and Gram-negative organisms. It is primarily utilized in pharmaceutical research, development, and manufacturing for the formulation of sterile injectable antibiotic products.

Application

• Active Pharmaceutical Ingredient (API) for injectable antibiotic formulations.
• Pharmaceutical Intermediates in the synthesis of more complex cephalosporin derivatives.
• Microbiological Research as a standard or reference compound for studying bacterial resistance and efficacy.
• Veterinary Medicine for developing treatments for bacterial infections in animals.
• Clinical Trial Materials for evaluating new dosage forms or combination therapies.

Basic Information

Product Name	Cefamandole Sodium
CAS No.	52079-92-2
Molecular Formula	C18H17N6NaO5S2
Molecular Weight	484.48 g/mol
Synonyms	Cefamandole Sodium; Cefamandole Nafate (common salt form); Mandol; (6R,7R)-7-[[(2R)-2-Hydroxy-2-phenylacetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt; Cefamandolum Natricum; Sodium (6R,7R)-7-[(2R)-2-hydroxy-2-phenylacetamido]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Cefamandole Sodium is manufactured and tested under strict quality systems. Each batch is analyzed to meet high-purity standards suitable for pharmaceutical applications, with specifications referencing pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (Solution)	6.0 - 8.0
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.