Description

Taipoxin CAS NO 52019-39-3 is a potent, high-molecular-weight neurotoxin complex isolated from the venom of the Australian taipan snake (*Oxyuranus scutellatus*). This compound is of significant value in neuroscience and pharmacological research due to its highly specific and irreversible inhibition of presynaptic neurotransmitter release. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers for studying neuromuscular junctions, synaptic vesicle recycling, and as a critical tool in developing assays for neurological function.

Application

• Neuroscience Research: A primary tool for studying the molecular mechanisms of presynaptic neurotoxicity, acetylcholine release, and synaptic transmission.
• Pharmacological Studies: Used to investigate and characterize potential antidotes, therapeutic agents, and the pathophysiology of neurotoxic envenoming.
• Diagnostic Reagent Development: Serves as a key component in the development of highly specific in-vitro assays and test kits for detecting and quantifying neurotoxic activity.
• Cell Biology & Physiology: Employed in experimental models to probe calcium channel function, vesicle fusion processes, and cell signaling pathways at the neuromuscular junction.
• Toxicology & Venom Research: Used as a reference standard for comparative studies of snake venoms and for the quality control of antivenom production.

Basic Information

Product Name	Taipoxin
CAS No.	52019-39-3
Molecular Formula	Contact for details
Molecular Weight	~45,600 Da (Complex)
Synonyms	Taipan Venom Toxin; Presynaptic Neurotoxin Complex; Oxyuranus scutellatus Toxin; Taipoxin Complex; Phospholipase A2 Neurotoxin; β-Bungarotoxin-like Toxin; Taipan Snake Neurotoxin; PLA2 Neurotoxin Complex
EINECS	Contact for details

Quality Control

Every batch of Taipoxin is subjected to rigorous analytical characterization to ensure identity, purity, and consistent biological activity. Our quality protocols include assessment by SDS-PAGE, HPLC, and functional bioactivity assays. A comprehensive Certificate of Analysis (COA) detailing purity, specific activity, and test results is provided with each shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store frozen at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, solutions should be aliquoted to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Consistent banding pattern of three subunits (α, β, γ)
Purity (HPLC)	≥ 90% (Protein basis)
Protein Content (BCA)	≥ 85%
Specific Activity (Mouse LD50)	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers or saline

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.