Description

Methyl n-(3-Amino-2,4,6-Triiodobenzoyl)-n-Phenyl-β-Alaninate is a specialized iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. This high-purity intermediate is critical for ensuring the final pharmaceutical product's efficacy and safety profile. It is essential for manufacturers in the pharmaceutical and diagnostic imaging industries who require reliable, high-quality building blocks for complex contrast agent production.

Application

• Primary Intermediate for X-ray Contrast Media: A crucial building block in the synthesis of non-ionic, low-osmolar contrast agents used in angiography, urography, and computed tomography (CT) scans.
• Pharmaceutical Research & Development: Serves as a key starting material or intermediate in the R&D of novel iodinated diagnostic compounds.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of final API molecules for injectable contrast solutions.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical laboratories.
• Specialty Chemical Synthesis: Potential use in creating other iodinated aromatic compounds for various research applications.

Basic Information

Product Name	Methyl n-(3-Amino-2,4,6-Triiodobenzoyl)-n-Phenyl-β-Alaninate
CAS No.	51934-66-8
Molecular Formula	C17H15I3N2O3
Molecular Weight	683.03 g/mol
Synonyms	Methyl 3-[[(3-Amino-2,4,6-triiodobenzoyl)amino]-N-phenyl]propanoate; Benzoic acid, 3-amino-2,4,6-triiodo-, 3-[(methoxycarbonyl)ethyl]phenylamide; N-(3-Amino-2,4,6-triiodobenzoyl)-N-phenyl-β-alanine methyl ester; Iopamidol Intermediate; Contrast Agent Intermediate; 51934-66-8; 3-Amino-2,4,6-triiodo-N-[3-(methoxycarbonyl)propyl]-N-phenylbenzamide
EINECS	Contact for details

Quality Control

Our Methyl n-(3-Amino-2,4,6-Triiodobenzoyl)-n-Phenyl-β-Alaninate is manufactured under strict quality management systems suitable for pharmaceutical intermediate production. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications. Certificates of Analysis (COA) are provided with each shipment, detailing all critical quality attributes. We support compliance with cGMP, ICH Q7 guidelines, and relevant pharmacopeial standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.