Description

Prochlorperazine Mesylate Bp is a high-purity pharmaceutical active ingredient, a mesylate salt form of the phenothiazine derivative prochlorperazine. This compound is critical for ensuring the efficacy and safety of finished pharmaceutical formulations, serving as a key building block for reliable antiemetic and antipsychotic therapies. It is primarily required by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development and production of injectable and other sterile dosage forms.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of finished dosage forms, particularly injectable solutions.
• Antiemetic Medication: Core component in drugs prescribed to prevent and treat severe nausea and vomiting, often associated with chemotherapy, surgery, or migraine.
• Antipsychotic Therapy: Used in the management of schizophrenia and other psychotic disorders where the mesylate salt form is indicated.
• Reference Standard: Serves as a high-purity chemical standard for quality control laboratories performing HPLC, UV, or titration assays.
• Research & Development: Utilized in preclinical and clinical studies for investigating neurological pathways and developing new therapeutic approaches.
• Generic Drug Manufacturing: Essential for companies producing bioequivalent versions of branded prochlorperazine medications.

Basic Information

Product Name	Prochlorperazine Mesylate Bp
CAS No.	51888-09-6
Molecular Formula	C₂₀H₂₄ClN₃S • CH₄O₃S
Molecular Weight	473.99 g/mol
Synonyms	Prochlorperazine Methanesulfonate; Compazine Mesylate; 2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine Methanesulfonate; Prochlorperazine Mesilate; NSC-77690; Plegomazine; Stemetil; Vertigon; Chlorperazine Mesylate
EINECS	Contact for details

Quality Control

Our Prochlorperazine Mesylate Bp is manufactured and tested to meet or exceed the standards of the British Pharmacopoeia (BP). Every batch undergoes rigorous quality testing including identity confirmation, purity assay, and impurity profiling to ensure compliance with stringent pharmaceutical requirements. Certificates of Analysis (COA) documenting full specifications are available upon request to support your regulatory and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 5.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.