Description

β-Chloro-D-Alanine Hydrochloride is a high-purity, non-proteinogenic amino acid derivative of significant value in advanced chemical synthesis and pharmaceutical research. Its primary importance lies in its role as a versatile chiral building block and a potent enzyme inhibitor, specifically targeting alanine racemase and other pyridoxal phosphate-dependent enzymes. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing novel antibiotics, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new antibacterial agents and enzyme-targeted therapeutics.
• Biochemical Research: Used as a mechanism-based irreversible inhibitor of alanine racemase, a critical enzyme in bacterial cell wall biosynthesis, for microbiological and enzymological studies.
• Agrochemical Synthesis: Serves as a precursor in the synthesis of specialized amino acid-based herbicides and plant growth regulators.
• Peptide Chemistry: Incorporated into synthetic peptides to study structure-activity relationships or to create peptides with modified properties.
• Diagnostic Reagent Development: Employed in the formulation of enzyme assay kits and diagnostic reagents for clinical and research laboratories.
• Academic & Industrial R&D: A fundamental reagent for organic synthesis and medicinal chemistry projects exploring novel bioactive compounds.

Basic Information

Product Name	β-Chloro-D-Alanine Hydrochloride
CAS No.	51887-88-8
Molecular Formula	C₃H₇Cl₂NO₂
Molecular Weight	184.00 g/mol
Synonyms	(R)-3-Chloro-2-aminopropanoic acid hydrochloride; D-3-Chloroalanine hydrochloride; (R)-3-Chloroalanine hydrochloride; D-β-Chloroalanine hydrochloride; (2R)-2-Amino-3-chloropropanoic acid hydrochloride; NSC 132953; β-Chloro-D-alanine HCl; BOC-D-3-Chloroalanine
EINECS	Contact for details

Quality Control

Our β-Chloro-D-Alanine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable, and our quality standards are designed to meet the rigorous demands of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.