Description

n-Boc-1,6-Diaminohexane is a protected diamine derivative featuring a tert-butoxycarbonyl (Boc) group, a crucial building block in organic synthesis and pharmaceutical research. Its primary value lies in providing a reactive primary amine handle while protecting the other, enabling selective and sequential peptide coupling and polymer modification reactions. This compound is essential for researchers and manufacturers in medicinal chemistry, polymer science, and bioconjugation who require high-purity intermediates for the development of novel compounds and materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating peptide-based drugs and drug-linker conjugates.
• Peptide Synthesis: Serves as a spacer or linker molecule in solid-phase and solution-phase peptide synthesis, introducing a hexyl chain into the peptide backbone.
• Polymer Chemistry: Used as a monomer or cross-linking agent in the production of polyamides, polyurethanes, and other specialty polymers with tailored properties.
• Bioconjugation: Facilitates the attachment of dyes, probes, or other molecules to proteins, antibodies, or nanoparticles for diagnostic and research applications.
• Organic Synthesis: A versatile reagent for introducing protected amine functionalities into complex organic molecules and macrocycles.
• Material Science: Employed in the surface functionalization of materials and the creation of amine-reactive coatings and hydrogels.

Basic Information

Product Name	n-Boc-1,6-Diaminohexane
CAS No.	51857-17-1
Molecular Formula	C11H24N2O2
Molecular Weight	216.32 g/mol
Synonyms	1,6-Hexanediamine, N-Boc derivative; N1-Boc-1,6-diaminohexane; N-(tert-Butoxycarbonyl)-1,6-hexanediamine; 6-[(tert-Butoxycarbonyl)amino]hexan-1-amine; Boc-1,6-diaminohexane; Boc-HDA; tert-Butyl (6-aminohexyl)carbamate; 1,6-Diaminohexane mono-Boc protected
EINECS	Contact for details

Quality Control

Our n-Boc-1,6-Diaminohexane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to minimize moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.