Description

Angiotensin 1/2 + A (2 - 8) CAS NO 51833-76-2 is a synthetic peptide fragment related to the renin-angiotensin system, a critical regulator of blood pressure and fluid balance. This compound is of significant value as a high-purity biochemical tool and a key intermediate in advanced pharmaceutical research and development. It is primarily required by biotechnology companies, academic research institutions, and pharmaceutical manufacturers engaged in cardiovascular research, peptide synthesis, and the development of diagnostic assays.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of the renin-angiotensin-aldosterone system (RAAS) and its role in hypertension.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of longer angiotensin-related peptides or analogs for drug discovery.
• Diagnostic Development: Employed in the development and calibration of immunoassays (e.g., ELISA) to measure angiotensin peptides in biological samples.
• Enzyme Substrate Studies: Acts as a substrate for investigating the activity and inhibition of angiotensin-converting enzyme (ACE) and other proteases.
• Cell Signaling & Receptor Binding: Utilized in vitro and in vivo experiments to study angiotensin receptor (AT1, AT2) interactions and downstream signaling pathways.
• Quality Control Standards: Provides a certified reference material for ensuring the accuracy and consistency of peptide-based pharmaceutical products.

Basic Information

Product Name	Angiotensin 1/2 + A (2 - 8)
CAS No.	51833-76-2
Molecular Formula	C41H62N12O11
Molecular Weight	898.99 g/mol
Synonyms	Angiotensin I/II (2-8); Angiotensin (2-8); Asp-Arg-Val-Tyr-Ile-His-Pro; DRVYIHP; [Asp1, Arg2, Val3, Tyr4, Ile5, His6, Pro7]-Angiotensin I/II; Angiotensin Fragment 2-8
EINECS	Contact for details

Quality Control

Our Angiotensin 1/2 + A (2 - 8) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, peptide content, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.