Description

Sodium Cefoxitin is a semi-synthetic, broad-spectrum cephamycin antibiotic derived from cephamycin C. This second-generation cephalosporin is valued for its stability against β-lactamase enzymes, making it effective against a wide range of Gram-positive and Gram-negative bacteria. It is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the production of injectable antibiotic formulations. Sodium Cefoxitin CAS NO 51829-86-8 is supplied as a high-purity, sterile-grade powder.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable antibiotic products.
• Hospital Infection Control: Formulated for the treatment of severe infections including intra-abdominal, gynecological, and skin structure infections.
• Surgical Prophylaxis: Used to prevent post-operative infections, particularly in colorectal and obstetric-gynecologic surgeries.
• Bacteriological Research: Serves as a reference standard and as a selective agent in microbiological culture media.
• Veterinary Medicine: Employed in the treatment of bacterial infections in animals under veterinary supervision.

Basic Information

Product Name	Sodium Cefoxitin
CAS No.	51829-86-8
Molecular Formula	C16H16N3NaO7S2
Molecular Weight	449.43 g/mol
Synonyms	Cefoxitin Sodium; Sodium 3-{[(aminocarbonyl)oxy]methyl}-7α-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; (6R,7S)-3-(Carbamoyloxymethyl)-7-methoxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt; Mefoxin; Cefoxitin Sodium Salt; Cefoxitin Na
EINECS	257-452-5

Quality Control

Our Sodium Cefoxitin is manufactured under cGMP conditions and undergoes rigorous analytical testing to ensure it meets the highest standards for pharmaceutical use. Quality is verified against relevant pharmacopeial monographs (USP/EP). A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing purity, potency, and impurity profiles to ensure supply reliability and regulatory compliance for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	96.0% - 102.0% (on anhydrous basis)
pH (10% solution)	4.0 - 7.0
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Sterility (where applicable)	Sterile
Bacterial Endotoxins	< 0.10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.