Description

Benzonitrile, 2-Chloro-3-Hydroxy- is a versatile halogenated and hydroxylated aromatic nitrile derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both an electron-withdrawing nitrile group and reactive chloro and hydroxyl substituents, makes it an indispensable intermediate for creating complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for fine chemical producers engaged in custom synthesis projects for global clients.

Basic Information

Item	Detail
Product Name	Benzonitrile, 2-Chloro-3-Hydroxy-
CAS No.	51786-11-9
Molecular Formula	C7H4ClNO
Molecular Weight	153.56 g/mol
Synonyms	2-Chloro-3-hydroxybenzonitrile; 3-Hydroxy-2-chlorobenzonitrile; 2-Chloro-3-cyanophenol; 2-Chloro-3-hydroxyphenyl cyanide; 3-Cyano-2-chlorophenol; 2-Chloro-3-hydroxybenzenecarbonitrile; 2-Chloro-3-phenol carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Hydroxybenzonitrile is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR and NMR), and impurity profile is provided with each shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.