Description

4-(4-Bromophenyl)-4-Oxobutyronitrile is a versatile brominated aromatic nitrile ketone intermediate of significant importance in advanced organic synthesis. Its unique bifunctional structure, featuring both a ketone and a nitrile group, makes it a valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those with brominated aromatic cores for receptor binding studies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Building block for novel organic electronic materials, liquid crystals, and polymers due to its conjugated system.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific bromo-functionalized intermediate.

Basic Information

Product Name	4-(4-Bromophenyl)-4-Oxobutyronitrile
CAS No.	51765-77-6
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	4-(4-Bromobenzoyl)propionitrile; 4-(p-Bromobenzoyl)butyronitrile; 4-(4-Bromobenzoyl)butyronitrile; 4-Oxo-4-(4-bromophenyl)butanenitrile; 4-Bromophenyl 2-cyanoethyl ketone; γ-Oxo-4-bromobenzenebutanenitrile; p-Bromobenzoylpropionitrile
EINECS	Contact for details

Quality Control

Our production of 4-(4-Bromophenyl)-4-Oxobutyronitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We are committed to meeting the exacting standards required for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.