Description

Sodium Hydrogen [6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-[(5-Amino-5-Carboxylato-1-Oxopentyl)Amino]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate is the sodium salt of a key intermediate in the synthesis of advanced cephalosporin antibiotics. This compound is critical for ensuring the structural integrity and biological activity of the final active pharmaceutical ingredient (API). It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of next-generation β-lactam antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: As a crucial building block in the synthesis of advanced-generation cephalosporin antibiotics.
• API Manufacturing: Used in the production of active pharmaceutical ingredients for injectable antibiotic formulations.
• Research & Development: Serves as a key reference standard and starting material in antimicrobial research and new drug development.
• Process Chemistry: Employed in scale-up and optimization studies for efficient antibiotic production.
• Quality Control: Utilized as an analytical standard for impurity profiling and assay validation of cephalosporin drugs.

Basic Information

Product Name	Sodium Hydrogen [6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-[(5-Amino-5-Carboxylato-1-Oxopentyl)Amino]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
CAS No.	51762-04-0
Molecular Formula	C20H24N4NaO9S
Molecular Weight	519.48 g/mol
Synonyms	(6R,7R)-7-[(R)-2-Amino-2-carboxyacetamido]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt; Sodium 7β-[(R)-2-Amino-2-carboxyacetamido]-3-(acetoxymethyl)-3-cephem-4-carboxylate; Cephalosporin C Sodium Salt derivative; 7-ADCA side chain intermediate sodium salt; GL-7-ACA sodium salt derivative; Sodium (6R,7R)-7-[(R)-2-Amino-2-hydroxyacetyl]amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate acetate
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and related substances, NMR for structural confirmation, and stringent limits for residual solvents and heavy metals, to ensure compliance with ICH guidelines. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C limits
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.