Description

Trifluoromethanesulfinyl Isocyanate is a highly reactive and versatile fluorinated building block used in advanced organic synthesis. This compound is critical for introducing the trifluoromethanesulfinyl (CF3SO-) moiety, which can impart unique electronic and steric properties to target molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent for synthesizing sulfinamide and sulfonylurea derivatives with potential biological activity.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that benefit from fluorine's metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral sulfinyl ligands used in asymmetric catalysis.
• Polymer Modification: Employed to introduce fluorinated functional groups into polymers to enhance thermal stability, chemical resistance, or surface properties.
• Organic Electronics: Building block for synthesizing charge-transport or emissive materials in OLEDs and other electronic devices.
• Peptide and Protein Research: Can be used for selective modification of amino acid side chains under mild conditions.

Basic Information

Product Name	Trifluoromethanesulfinyl Isocyanate
CAS No.	51735-89-8
Molecular Formula	C2F3NO2S
Molecular Weight	159.09 g/mol
Synonyms	Trifluoromethanesulfinyl Isocyanate; Isocyanato(trifluoromethyl)sulfane; Trifluoromethylsulfinyl Isocyanate; CF3S(O)NCO; (Trifluoromethyl)sulfinyl Isocyanate; Trifluoromethanesulfinyl Carbimide; Trifluoromethylsulfinyl Carbodiimide (common misnomer); TFSO-NCO
EINECS	Contact for details

Quality Control

Our Trifluoromethanesulfinyl Isocyanate is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including purity assay and impurity profiling by GC and NMR, to ensure consistency and reliability for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this material should be stored under a dry, inert atmosphere (e.g., nitrogen or argon) at recommended temperatures between 2°C and 8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress and pressure changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.