Description

Trifluoro-n-(Trimethylsilyl)Methanesulfinamide is a specialized organosilicon reagent featuring a unique trifluoromethylsulfinamide group protected by a trimethylsilyl moiety. This compound is highly valued in advanced organic synthesis for its role as a versatile building block and fluorinating agent, enabling the introduction of fluorine atoms and sulfinamide functionalities into complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated bioactive molecules, including potential APIs (Active Pharmaceutical Ingredients).
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with enhanced properties through fluorination.
• Fluorination Reagent: Acts as a source of the trifluoromethylsulfinyl group in nucleophilic or electrophilic fluorination reactions.
• Sulfinamide Protection: The trimethylsilyl group serves as a protecting group for the sulfinamide nitrogen, allowing for selective deprotection in multi-step syntheses.
• Material Science Research: Employed in the synthesis of fluorinated polymers or specialty materials with specific surface or electronic properties.
• Cross-Coupling & Functionalization: Utilized in metal-catalyzed reactions to introduce functional handles for further molecular elaboration.

Basic Information

Product Name	Trifluoro-n-(Trimethylsilyl)Methanesulfinamide
CAS No.	51735-79-6
Molecular Formula	C4H10F3NOSSi
Molecular Weight	197.28 g/mol
Synonyms	N-(Trimethylsilyl)trifluoromethanesulfinamide; Trimethylsilyl Trifluoromethanesulfinimide; (Trimethylsilyl)trifluoromethanesulfinamide; TMS-Protected Trifluoromethanesulfinamide; S,S,S-Trifluoro-N-(trimethylsilyl)methanesulfinamide; N-Trimethylsilyl-perfluoro-tert-butylamine related sulfinamide; Trifluoromethanesulfinamide, N-(trimethylsilyl)-
EINECS	Contact for details

Quality Control

Our Trifluoro-n-(Trimethylsilyl)Methanesulfinamide is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is assured through rigorous analytical testing, including NMR, GC, and HPLC analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic and fluoride/strong alkali nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.