Description

n-Nitrosochlordiazepoxide is a specific chemical derivative of the benzodiazepine class, identified by CAS No. 51715-17-4. This compound is of significant interest in pharmaceutical research and development, particularly for analytical and metabolic studies. It serves as a critical reference standard and intermediate for researchers and manufacturers in the life sciences sector who require high-purity, well-characterized compounds for method development and quality control.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the identification, assay, and impurity profiling of related active pharmaceutical ingredients (APIs) in quality control laboratories.
• Metabolite Research: Employed in pharmacokinetic and metabolic pathway studies to understand the biotransformation of parent drug compounds.
• Analytical Method Development: Serves as a key component in developing and validating chromatographic methods (e.g., HPLC, LC-MS) for drug analysis.
• Chemical Intermediate: Acts as a specialized synthetic building block for the research-scale preparation of novel benzodiazepine analogues.
• Forensic and Toxicology Analysis: Utilized as a calibrant or control material in forensic laboratories for the detection and quantification of specific substances.

Basic Information

Product Name	n-Nitrosochlordiazepoxide
CAS No.	51715-17-4
Molecular Formula	C16H14ClN3O3
Molecular Weight	331.75 g/mol
Synonyms	7-Chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine 4-oxide; 7-Chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide; N-Nitrosochlordiazepoxide; Chlordiazepoxide N-oxide; Chlordiazepoxide impurity; Librium derivative; Ro 5-4556 (historical code)
EINECS	Contact for details

Quality Control

Our n-Nitrosochlordiazepoxide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for research and reference materials. A detailed Certificate of Analysis (COA) providing results for assay, related substances, and identification tests is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.