Description

3-[(Difluoromethyl)Sulfonyl]Bromobenzene is a specialized organobromine and organosulfur compound featuring a difluoromethylsulfonyl substituent. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in the development of novel active ingredients. It is primarily utilized by pharmaceutical and agrochemical R&D teams seeking to incorporate fluorinated sulfone motifs into target molecules to modulate their biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates requiring fluorinated aromatic sulfones.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the difluoromethylsulfonyl group can enhance efficacy and environmental profile.
• Material Science Research: Serves as a precursor for synthesizing specialty polymers, ligands, or functional materials with specific electronic properties.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form complex biaryl structures.
• Fluorine Chemistry Studies: Employed in academic and industrial research focused on the synthesis and reactivity of fluorinated organic compounds.

Basic Information

Product Name	3-[(Difluoromethyl)Sulfonyl]Bromobenzene
CAS No.	51679-56-2
Molecular Formula	C7H5BrF2O2S
Molecular Weight	271.08 g/mol
Synonyms	1-Bromo-3-[(difluoromethyl)sulfonyl]benzene; 3-Bromophenyl difluoromethyl sulfone; m-Bromophenyl difluoromethyl sulfone; Benzene, 1-bromo-3-[(difluoromethyl)sulfonyl]-; (3-Bromophenyl)(difluoromethyl)sulfone
EINECS	Contact for details

Quality Control

Our 3-[(Difluoromethyl)Sulfonyl]Bromobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.