Description

tert-Butyldiisopropylphosphine is a highly specialized organophosphorus compound prized for its role as a sterically demanding and electron-rich ligand. Its primary value lies in enabling highly efficient and selective catalytic transformations, particularly in cross-coupling reactions. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over reaction pathways and product purity.

Application

• As a key ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi, Buchwald-Hartwig amination) for C-C and C-N bond formation.
• Catalyst component in the synthesis of active pharmaceutical ingredients (APIs) and complex organic intermediates.
• Precursor for the development of specialized catalysts used in fine chemical and polymer production.
• Research and development of new organometallic complexes for asymmetric synthesis and material science applications.
• Use in agrochemical research for creating novel, high-performance compounds.
• Component in homogeneous catalysis systems requiring high activity and selectivity under mild conditions.

Basic Information

Product Name	tert-Butyldiisopropylphosphine
CAS No.	51567-05-6
Molecular Formula	C10H23P
Molecular Weight	174.26 g/mol
Synonyms	Diisopropyl(tert-butyl)phosphine; t-BuP(i-Pr)2; tert-Butyldiisopropylphosphane; (1,1-Dimethylethyl)bis(1-methylethyl)phosphine; JohnPhos (Note: JohnPhos is a specific, related ligand; this is a common search term); P(t-Bu)(i-Pr)2; Phosphine, (1,1-dimethylethyl)bis(1-methylethyl)-; Ligand for cross-coupling
EINECS	Contact for details

Quality Control

Our tert-Butyldiisopropylphosphine is produced under stringent conditions to ensure high purity and consistency, critical for sensitive catalytic applications. Each batch is analyzed using advanced techniques like NMR and GC to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and easily oxidized nature, this material must be stored and handled under an inert atmosphere (argon or nitrogen) at temperatures between 2°C and 8°C. Keep the container tightly sealed in a cool, dry, and well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.