Description

2-Propanone, 1-Bromo-3-Fluoro- is a specialized halogenated acetone derivative, also known as 1-Bromo-3-fluoroacetone. This compound serves as a versatile and valuable building block in advanced organic synthesis, particularly for introducing functionalized alkyl chains. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create complex molecules for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated and brominated drug candidates, including potential antiviral and anticancer agents.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and pesticides with enhanced biological activity and selectivity.
• Fluorinated Compound Research: A critical reagent in medicinal chemistry for exploring structure-activity relationships (SAR) by introducing both fluorine and bromine atoms.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and complex organic materials.
• Cross-Coupling Reactions: Serves as an electrophile in various palladium-catalyzed and other metal-mediated coupling reactions.
• Bioconjugation & Labeling: Potential use in modifying biomolecules for research and diagnostic applications due to its reactive carbonyl and halogen groups.

Basic Information

Product Name	2-Propanone, 1-Bromo-3-Fluoro-
CAS No.	51483-48-8
Molecular Formula	C3H4BrFO
Molecular Weight	154.97 g/mol
Synonyms	1-Bromo-3-fluoroacetone; 3-Fluoro-1-bromoacetone; 3-Fluorobromoacetone; 1-Bromo-3-fluoropropan-2-one; Bromofluoroacetone; α-Bromo-β-fluoroacetone; Acetone, 1-bromo-3-fluoro-; 51483-48-8
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1-Bromo-3-Fluoro- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is 2-8°C for extended stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatility.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.