Description

Sodium [6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-(Hydroxyphenylacetamido)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate is the sodium salt of a key cephalosporin intermediate, essential for the synthesis of advanced β-lactam antibiotics. This high-purity compound is critical for ensuring the efficacy and safety of the final active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of cephalosporin-class antibiotics.

Application

• Pharmaceutical Intermediate: A crucial building block in the chemical synthesis of second and third-generation cephalosporin antibiotics.
• API Manufacturing: Used in the production of active pharmaceutical ingredients (APIs) such as cefazolin, cefuroxime, and related compounds.
• Research & Development: Serves as a key starting material in medicinal chemistry for developing novel β-lactam structures and studying structure-activity relationships.
• Process Chemistry: Employed in scale-up and optimization of antibiotic synthesis routes within GMP-compliant facilities.
• Reference Standard: Can be utilized as a high-purity standard for analytical method development and quality control testing of cephalosporin products.

Basic Information

Product Name	Sodium [6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-(Hydroxyphenylacetamido)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
CAS No.	51372-87-3
Molecular Formula	C19H18N3NaO7S
Molecular Weight	455.42 g/mol
Synonyms	7-ACA Sodium Salt (Acetoxy Derivative); Sodium 3-(Acetoxymethyl)-7-(2-hydroxy-2-phenylacetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cephalosporin 7-ACA Sodium Ester; 7-Aminocephalosporanic Acid Sodium Salt (Acetyloxymethyl Ester); Sodium 7-ACA Acetoxymethyl Ester; 7-ACA Sodium Acetoxymethyl Ester; (6R,7R)-3-(Acetoxymethyl)-7-[(R)-2-Hydroxy-2-phenylacetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt
EINECS	Contact for details

Quality Control

Our Sodium [6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-(Hydroxyphenylacetamido)-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and chemical identity consistent with pharmaceutical intermediate requirements. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.