Description

2-Hydroxy-5-Methylbenzonitrile is a versatile aromatic nitrile derivative with a phenolic hydroxyl group, serving as a key synthetic intermediate in advanced organic chemistry. Its molecular structure makes it a valuable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals. This high-purity compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable building blocks for heterocyclic synthesis and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various drug candidates, particularly those containing benzoxazole, quinazoline, or other fused heterocyclic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its nitrile and phenolic functionalities are key.
• Dye and Pigment Manufacturing: Serves as a precursor for synthesizing specialized azo dyes and high-performance pigments.
• Ligand and Catalyst Development: Utilized in research for creating novel chelating ligands and organocatalysts due to its donor-acceptor properties.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of specialty polymers, including polyesters and polyamides with specific thermal or optical properties.
• Material Science Research: Employed in the development of organic electronic materials, such as OLED components or molecular sensors.

Basic Information

Item	Details
Product Name	2-Hydroxy-5-Methylbenzonitrile
CAS No.	51282-90-7
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	5-Methyl-2-hydroxybenzonitrile; 2-Cyano-4-methylphenol; 4-Methyl-2-cyanophenol; 6-Hydroxy-m-tolunitrile; 2-Hydroxy-5-methylbenzenecarbonitrile; 5-Methylsalicylonitrile; o-Hydroxy-p-tolunitrile
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-5-Methylbenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our production facilities and processes are designed to meet the stringent requirements of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.