Description

Parathyroid Hormone (3-34) is a bioactive fragment of the native parathyroid hormone, specifically the 3-34 amino acid sequence. This synthetic peptide is a critical research tool for studying calcium and phosphate metabolism, bone biology, and the structure-activity relationships of PTH receptors. It is essential for pharmaceutical R&D, academic research, and diagnostic development in the fields of endocrinology and metabolic bone diseases.

Application

• Biomedical Research: Used as a standard and probe in studies of PTH receptor (PTH1R) binding, activation, and downstream signaling pathways.
• Drug Discovery: Serves as a reference compound and starting point for the development of novel therapeutics targeting osteoporosis, hyperparathyroidism, and hypoparathyroidism.
• Endocrinology Studies: Investigates the role of PTH in calcium homeostasis, renal phosphate handling, and bone remodeling processes.
• In Vitro Diagnostics (IVD): Potential use as a calibrator or control in assay development for measuring PTH-related peptides.
• Academic & Clinical Research: Fundamental tool for understanding the molecular mechanisms of bone diseases and evaluating new treatment strategies.

Basic Information

Product Name	Parathyroid Hormone (3-34)
CAS No.	51257-86-4
Molecular Formula	C152H246N44O45S2
Molecular Weight	3482.9 g/mol
Synonyms	PTH (3-34); Parathyroid Hormone Fragment 3-34; Human Parathyroid Hormone (3-34); hPTH (3-34); PTH 3-34 amide; [Tyr34]hPTH(3-34)NH2; Parathyrin (3-34); Parathormone (3-34)
EINECS	Contact for details

Quality Control

Our Parathyroid Hormone (3-34) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and endotoxin levels are provided to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.