Description

4-Chloro-3-Nitrophenylacetonitrile is a versatile aromatic nitrile building block characterized by its chloro and nitro substituents. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries that require high-purity intermediates for research and production, such as fine chemical manufacturers and contract research organizations, are the primary users of this material.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those with complex heterocyclic structures.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, leveraging its reactive nitrile and halogenated aromatic system.
• Dye and Pigment Manufacturing: Serves as a building block for advanced colorants and functional dyes due to its nitro-aromatic backbone.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for creating biaryl structures.
• Chemical Research & Development: A valuable reagent for exploring new synthetic pathways and methodologies in academic and industrial labs.

Basic Information

Product Name	4-Chloro-3-Nitrophenylacetonitrile
CAS No.	51250-90-9
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	(4-Chloro-3-nitrophenyl)acetonitrile; 2-(4-Chloro-3-nitrophenyl)acetonitrile; 4-Chloro-3-nitrobenzyl cyanide; 4-Chloro-3-nitro-α-tolunitrile; 4-Chloro-3-nitrobenzeneacetonitrile; 4-Chloro-3-nitrobenzylnitrile; 4-Chloro-3-nitrophenylacetic acid nitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Nitrophenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.