Description

3-{[(Benzyloxy)Carbonyl]Amino}-3-Methylbutanoic Acid is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the sterically hindered 3-amino-3-methylbutanoic acid moiety into target molecules under controlled conditions. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), peptides, and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used to incorporate the sterically hindered 3-amino-3-methylbutanoic acid residue into custom peptides and peptidomimetics.
• Protecting Group Chemistry: The Cbz (carboxybenzyl) protecting group allows for selective deprotection in multi-step synthetic sequences.
• Bioconjugation & Linker Chemistry: Serves as a functionalized spacer or linker molecule in bioconjugate and probe development.
• Agrochemical Research: Intermediate in the synthesis of complex molecules for crop protection and agricultural chemicals.
• Academic & Industrial R&D: Essential reagent for methodological development and exploring new chemical spaces in organic chemistry.

Basic Information

Product Name	3-{[(Benzyloxy)Carbonyl]Amino}-3-Methylbutanoic Acid
CAS No.	51219-55-7
Molecular Formula	C13H17NO4
Molecular Weight	251.28 g/mol
Synonyms	3-[(Benzyloxycarbonyl)amino]-3-methylbutanoic acid; 3-Methyl-3-[(phenylmethoxy)carbonyl]aminobutanoic acid; 3-(Cbz-Amino)-3-methylbutyric acid; N-Cbz-3-amino-3-methylbutyric acid; N-Carbobenzoxy-3-amino-3-methylbutanoic acid; 3-Amino-3-methylbutyric acid N-carboxybenzyl derivative; Z-3-Amino-3-methylbutyric acid; (3-Methyl-3-{[(phenylmethyl)oxy]carbonyl}amino)butanoic acid
EINECS	Contact for details

Quality Control

Our 3-{[(Benzyloxy)Carbonyl]Amino}-3-Methylbutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for pharmaceutical and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.