Description

Butaclamol is a potent and selective dopaminergic agent belonging to the class of antipsychotic compounds. Its primary value lies in its use as a crucial pharmacological reference standard and research chemical for studying neurotransmitter receptors and neurological pathways. This compound is essential for pharmaceutical R&D laboratories, academic research institutions, and analytical facilities focused on neuroscience, psychopharmacology, and drug discovery.

Application

• Pharmacological Research: As a reference standard in studies of dopamine D1 and D2 receptor binding and antagonism.
• Neuroscience Studies: For investigating the biochemical and behavioral effects of dopaminergic modulation in animal models.
• Drug Discovery & Development: Serving as a key intermediate or active pharmaceutical ingredient (API) analog in the synthesis of novel therapeutic agents.
• Analytical Chemistry: Used as a high-purity standard for method development and validation in HPLC, LC-MS, and other chromatographic techniques.
• Biochemical Assays: Employed in in vitro screening assays to evaluate compound libraries for dopaminergic activity.
• Academic Teaching: Utilized in advanced university courses for practical demonstrations of receptor-ligand interactions.

Basic Information

Product Name	Butaclamol
CAS No.	51152-91-1
Molecular Formula	C25H31NO
Molecular Weight	361.52 g/mol
Synonyms	(+)-Butaclamol; (+)-1-(1,2,3,4,6,7,12,12b-Octahydro-2H-benzo[a]phenanthridin-2-yl)-1-butanone; Dexbutaclamol; NSC 169774; AY-23,028; Butaclamol Hydrochloride (salt form); 2-Butanone, 1-(1,2,3,4,6,7,12,12b-octahydro-2H-benzo[a]phenanthridin-2-yl)-, (2R,12bS)-rel-
EINECS	Contact for details

Quality Control

Our Butaclamol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods, and residual solvent analysis to ensure it meets the stringent requirements for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.