Description

4-Fluoro-1H-Isoindole-1,3(2H)-Dione is a specialized fluorinated isoindole derivative, a high-value building block in advanced organic synthesis. Its core value lies in providing a reactive, fluorinated aromatic scaffold that can significantly alter the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where the introduction of fluorine is a key design strategy. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, potentially for central nervous system (CNS) agents, kinase inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides where fluorination enhances stability and bioavailability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, dyes, and organic electronic materials.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle or tag in the design of chemical probes for studying enzyme activity and protein interactions.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry, particularly in cross-coupling and fluorination reactions.

Basic Information

Product Name	4-Fluoro-1H-Isoindole-1,3(2H)-Dione
CAS No.	51108-29-3
Molecular Formula	C8H4FNO2
Molecular Weight	165.12 g/mol
Synonyms	4-Fluoroisoindoline-1,3-dione; 4-Fluorophthalimide; 1H-Isoindole-1,3(2H)-dione, 4-fluoro-; 4-Fluoro-2,3-dihydro-1H-isoindole-1,3-dione; 4-Fluorophthalic acid imide; 4-Fluoroisoindoline-1,3-dione; 4-Fluoro-1H-isoindole-1,3(2H)-dione
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1H-Isoindole-1,3(2H)-Dione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.