Description

Iotroxic Acid CAS NO 51022-74-3 is a high-purity, iodinated organic compound primarily used as a key intermediate in the synthesis of X-ray contrast media. Its precise chemical structure is critical for ensuring the efficacy and safety of the final diagnostic agents. This product is essential for pharmaceutical manufacturers and advanced research laboratories focused on developing and producing non-ionic, low-osmolar contrast media for enhanced patient safety during radiographic procedures.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of iotroxate meglumine and related iodinated contrast agents.
• X-ray Contrast Media Production: Manufacture of diagnostic imaging agents for cholecystography (imaging of the gallbladder and biliary tract).
• Research & Development: Used in academic and industrial R&D for developing new generations of radiographic contrast materials with improved safety profiles.
• Chemical Synthesis: Serves as a specialized intermediate in organic synthesis for introducing iodinated aromatic structures.
• Quality Control Reference Standard: Employed as a reference compound in analytical laboratories for method development and impurity profiling in contrast media.

Basic Information

Product Name	Iotroxic Acid
CAS No.	51022-74-3
Molecular Formula	C22H18I6N2O9
Molecular Weight	1279.73 g/mol
Synonyms	Iotroxic Acid; 3,3'-(Adipoyldiimino)bis[2,4,6-triiodobenzoic acid]; Adipiodone Acid; Iotroxic Acid (USP); Iodoxamic Acid (related compound); Biligram Acid; Cholografin Acid; Iotroxate Acid; 3,3'-(Hexanedioyldiimino)bis(2,4,6-triiodobenzoic acid)
EINECS	256-980-1

Quality Control

Our Iotroxic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including identification, assay, and impurity profiling via HPLC, to ensure it meets high-purity standards suitable for pharmaceutical synthesis. Certificates of Analysis (COA) are provided with each shipment, detailing compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.