Description

n-(γ-L-Glutamyl)-1-Naphthylamide is a specialized biochemical reagent that serves as a chromogenic substrate for enzymatic assays. This compound is critical for research and quality control in fields requiring precise detection of γ-glutamyl transpeptidase (GGT) activity. It is primarily utilized by professionals in pharmaceutical development, clinical diagnostics, and biochemical research who require reliable and sensitive substrates for enzyme-linked studies.

Application

• Enzymatic Substrate for GGT: Primary use as a chromogenic substrate for the detection and quantification of γ-glutamyl transpeptidase activity in vitro.
• Clinical Diagnostics: Used in the formulation of diagnostic kits for measuring GGT levels in human serum, a key marker for liver and biliary tract function.
• Pharmaceutical Research: Employed in high-throughput screening (HTS) assays during drug discovery to identify compounds that modulate GGT activity.
• Biochemical Research: Essential tool for studying enzyme kinetics, inhibition, and the biochemical pathways involving glutathione metabolism.
• Quality Control in Manufacturing: Used in the QC labs of diagnostic kit manufacturers to validate batch consistency and assay performance.
• Academic Research: Applied in university and institutional labs for fundamental research into cellular processes, oxidative stress, and detoxification mechanisms.

Basic Information

Product Name	n-(γ-L-Glutamyl)-1-Naphthylamide
CAS No.	51012-91-1
Molecular Formula	C₁₉H₂₁N₃O₄
Molecular Weight	355.39 g/mol
Synonyms	L-γ-Glutamyl-1-naphthylamide; γ-Glutamyl-1-naphthylamide; 1-Naphthylamide, N-(L-γ-glutamyl)-; GGT Substrate; γ-Glutamyl-1-naphthylamide; N-(γ-L-Glutamyl)-1-naphthylamine; L-γ-Glutamyl-1-naphthylamide; N-(γ-L-Glutamyl)-1-naphthylamine
EINECS	Contact for details

Quality Control

Our n-(γ-L-Glutamyl)-1-Naphthylamide is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive diagnostic and research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Solubility	Soluble in DMSO, slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.