Description

Diatrizoic Acid Dihydrate is a high-purity, iodinated organic compound widely recognized as a key intermediate and active pharmaceutical ingredient (API) in diagnostic medicine. Its primary value lies in its role as a precursor for the synthesis of iodinated contrast media, which are essential for enhancing X-ray and CT imaging. This product is critically needed by pharmaceutical manufacturers, research institutions, and fine chemical suppliers serving the global medical diagnostics and healthcare sectors.

Application

• Pharmaceutical Intermediate: Primary use as a precursor in the synthesis of sodium and meglumine diatrizoate salts for X-ray contrast agents.
• Contrast Media Formulation: Direct formulation into ionic, water-soluble contrast media used in angiography, urography, and computed tomography (CT).
• Research & Development: Utilized in biochemical and pharmacological research to study contrast agent mechanisms and develop new diagnostic formulations.
• Reference Standard: Serves as a certified reference standard (CRS) for quality control and analytical method development in pharmaceutical labs.
• Fine Chemical Synthesis: Used as a building block in organic synthesis for other iodinated aromatic compounds.

Basic Information

Product Name	Diatrizoic Acid Dihydrate
CAS No.	50978-11-5
Molecular Formula	C11H9I3N2O4 • 2H2O
Molecular Weight	649.94 g/mol
Synonyms	3,5-Diacetamido-2,4,6-triiodobenzoic Acid Dihydrate; Amidotrizoic Acid Dihydrate; Diatrizoate Acid Dihydrate; Hypaque Acid; Gastrografin Acid; Urografin Acid; 3,5-Bis(acetylamino)-2,4,6-triiodobenzoic Acid Dihydrate
EINECS	Contact for details

Quality Control

Our Diatrizoic Acid Dihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profiles. Certificates of Analysis (COA) are provided with each shipment, detailing compliance with relevant in-house or pharmacopeial standards (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	4.5% - 6.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.