Description

3-(2-Bromoacetyl)Benzonitrile is a versatile and high-purity brominated aromatic ketone building block, essential for advanced organic synthesis. Its reactive bromoacetyl and nitrile functional groups make it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing benzofuran or indole cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for heterocycle formation.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of activity-based probes.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new reaction pathways in organic chemistry laboratories.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(2-Bromoacetyl)Benzonitrile
CAS No.	50916-55-7
Molecular Formula	C9H6BrNO
Molecular Weight	224.06 g/mol
Synonyms	2-Bromo-1-(3-cyanophenyl)ethanone; 3-(Bromoacetyl)benzonitrile; 1-(3-Cyanophenyl)-2-bromoethanone; m-Cyanophenacyl bromide; α-Bromo-3-cyanophenacyl bromide; 3-Cyanophenacyl bromide; 2-Bromo-3'-cyanophenacyl bromide
EINECS	Contact for details

Quality Control

Our 3-(2-Bromoacetyl)Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.