Description

3-(2H-Tetrazol-5-Yl)Benzonitrile is a versatile heterocyclic aromatic compound featuring a benzonitrile core substituted with a tetrazole ring, a key structural motif valued in advanced chemical synthesis. This compound matters as a critical pharmaceutical intermediate and ligand precursor in medicinal chemistry and materials science. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing tetrazole bioisosteres, which are important in cardiovascular and metabolic disease research.
• Medicinal Chemistry Research: Used as a core scaffold or precursor in drug discovery programs for designing novel enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Serves as an intermediate in the development of new herbicides, fungicides, and insecticides, where the tetrazole group can enhance biological activity and stability.
• Coordination Chemistry & Catalysis: Acts as a ligand precursor for metal-organic frameworks (MOFs) and catalysts, leveraging the tetrazole nitrogen atoms for metal coordination.
• Material Science: Employed in the research and development of advanced polymers, energetic materials, and corrosion inhibitors.
• Chemical Biology Probes: Utilized in the synthesis of probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	3-(2H-Tetrazol-5-Yl)Benzonitrile
CAS No.	50907-33-0
Molecular Formula	C8H5N5
Molecular Weight	171.16 g/mol
Synonyms	5-(3-Cyanophenyl)-1H-tetrazole; 3-(1H-Tetrazol-5-yl)benzonitrile; 3-Cyanophenyltetrazole; 3-Tetrazol-5-ylbenzonitrile; 1H-Tetrazole, 5-(3-cyanophenyl)-; Benzonitrile, 3-(2H-tetrazol-5-yl)-; 5-(3-Cyanophenyl)tetrazole
EINECS	Contact for details

Quality Control

Our 3-(2H-Tetrazol-5-Yl)Benzonitrile is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) with detailed specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.